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Asthma study using Apple's ResearchKit proven accurate when compared to existing research

A study reports ResearchKit is an extremely effective way to conduct medical research, with patient data collected from asthma sufferers via Apple's framework found to correlate with the results of similar studies using established data collection methods.

Researchers from the Icahn School of Medicine at Mount Sinai analyzed data from the Asthma Mobile Health Study, a program launched in March 2015 at the same time as Apple introduced ResearchKit itself. Unlike others, this study relied on just a specially-created iPhone app called Asthma Health, co-developed with LifeMap Solutions, which provided users with regular surveys concerning their health.

The app was downloaded almost 50,000 times in the first six months since its launch, according to results published in journal Nature Biotechnology. Of these downloads, a total of 7,593 people completed the electronic informed consent process, allowing data to be collected and analyzed by the researchers.

Out of the people completing the enrollment process, approximately 85 percent of users completed at least one survey offered by the app, which is a promising start. Ultimately, only 2,317 users from the enrolled pool filled out multiple surveys throughout the six-month study, but this was still a sufficient enough sample size for analysis.

The data was compared to the results of other asthma patient studies, with researchers noting common metrics between the sets of results, such as peak flow. Scientists were also able to correlate data from patients with external factors, including air quality, which also appeared to match existing studies.

Changes to the level of pollen and heat could also be corroborated in the study, when taking into account the user's location and other device data. For example, researchers were able to correlate increased daily asthma symptoms in Washington State with a wildfire outbreak, with the two occurring at similar times.

Yvonne Chan, Director of Digital Health and Personalized Medicine for Genomics and Multiscale Biology at Mount Sinai advises the use of iPhones and ResearchKit is "particularly suitable for studies of short duration that require rapid enrollment across diverse geographical locations, frequent data collection, and real-time feedback to participants."

"Our study demonstrates the power of mobile health tools to scale and accelerate clinical research so that we can derive the evidence needed to inform clinical practice and improve patient care."

Eric Schadt, Professor of Genomics at the Icahn School of Medicine and Founding Director of the Icahn Institute for Genomics and Multiscale Biology claims "We now have the ability to capture rich research data from thousands of individuals to better characterize 'real world' patterns of disease, wellness, and behavior. This approach provides a more comprehensive and accurate view of our patients that was not feasible in the past due to logistical limitations and prohibitive costs."

The study's results are likely to bolster ResearchKit's credibility as a framework for medical research, one that is already being used in a number of different projects. One recent study used the Apple Watch and ResearchKit to analyze seizure triggers in epilepsy sufferers, recording biometric data and prompting users to respond for reflex and awareness testing during each seizure event.



21 Comments

ireland 18 Years · 17436 comments

Asthma is repressed grief. People who work with the dying and their facility have known this for years. Deal with the grief and the asthma simply disappears. Human body evolved to heal itself, if only you let it. Peace out, Ireland.

rob53 13 Years · 3312 comments

I think what this demonstrates is that the majority of people are lazy, not willing to spend any time to manually enter information (except when they're using something more important like Facebook /s). The problem with studying asthma is that there isn't an automagic way of interpreting a person's reaction to external stimuli. I wish there was a way to capture asthma attacks, including what caused them. One way to get more people involved might be to talk about these products more often. I seem to remember reading about it but when I searched my iPhone, I didn't download the app, and when I search the App Store, Asthma Health, (using this term) is nowhere to be found. Clicking on the Asthma Health link above takes you to an AI article from May 2015 where only one person commented (@Ericthehalfbee). This is unfortunate and shows the general lack of self health care, especially by Americans. It's a lot easier to simply go to the ER and let someone else treat you.

(This is not a political statement and I'm not trying to make it one, I'm simply stating my opinion about the way too many people view health care.)

randominternetperson 8 Years · 3101 comments

ireland said:
Asthma is repressed grief. People who work with the dying and their facility have known this for years. Deal with the grief and the asthma simply disappears. Human body evolved to heal itself, if only you let it. Peace out, Ireland.

Uh... what? I know plenty of people with asthma and none of them is dealing with grief.

randominternetperson 8 Years · 3101 comments

rob53 said:
I think what this demonstrates is that the majority of people are lazy, not willing to spend any time to manually enter information (except when they're using something more important like Facebook /s). The problem with studying asthma is that there isn't an automagic way of interpreting a person's reaction to external stimuli. I wish there was a way to capture asthma attacks, including what caused them. One way to get more people involved might be to talk about these products more often. I seem to remember reading about it but when I searched my iPhone, I didn't download the app, and when I search the App Store, Asthma Health, (using this term) is nowhere to be found. Clicking on the Asthma Health link above takes you to an AI article from May 2015 where only one person commented (@Ericthehalfbee). This is unfortunate and shows the general lack of self health care, especially by Americans. It's a lot easier to simply go to the ER and let someone else treat you.

(This is not a political statement and I'm not trying to make it one, I'm simply stating my opinion about the way too many people view health care.)

On the glass-half-full side, over 2000 people were willing to take time to enter data into an app regularly for 6 months for a research study that offered no financial compensation or direct benefit for the user. Yay, research volunteers. I bet that people would be much more willing to track their data if it were part of a treatment plan coordinated by their personal physician.

ireland 18 Years · 17436 comments

Can't believe you guys deleted my asthma grief post. I've lots of experience about this. Nothing can be 'proven' in science so I won't be able to convince you, but it was totally relative and interesting to readers in my personal opinion. The least I could be given after 16,000 posts around here is a pinch of benefit of the doubt, even allowing others go disagree amicably. Or allowing the invitation to research the matter themselves. The human race cannot change otherwise. Wishing you all a pleasant year. Much respect.