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Apple partners with UCLA for three-year study on depression

Participants in the UCLA depression study will wear an Apple Watch in conjunction with an iPhone, with and end goal of revolutionizing the detection and treatment of depression.

The study will take place over three years and has been co-designed by researchers UCLA and Apple. The pilot phase will begin this week and involve 150 participants recruited from UCLA Health patients. The main phase will start in 2021 and run through 2023 and include 3,000 participants drawn from UCLA Health patients and the UCLA student body.

The study will utilize Apple technology, such as the iPhone and Apple Watch, as well as a Beddit sleep monitoring device. The study will measure how factors like sleep, physical activity, heart rate, and daily routines factor into depression and anxiety.

"As a neuroscientist by training with expertise in sleep, I am incredibly excited about this collaboration and am hopeful that it will lead to significant strides in mental health research," said UCLA Chancellor Gene Block.

As with heart health studies that Apple has done in the past, participants will need to download a research app on their iPhone. Apple Watches and Beddit sleep monitors will be provided for the duration of the study.

Participants will also be required to participate in clinical interviews and questionnaires. Researchers designed the study so all aspects can be accomplished remotely to avoid unnecessary exposure and spreading of the coronavirus.

Dr. Nelson Freimer, distinguished professor of psychiatry and director of the UCLA Depression Grand Challenge, is principal investigator on the study.

"This collaboration, which harnesses UCLA's deep research expertise and Apple's innovative technology, has the potential to transform behavioral health research and clinical care," Freimer said. "Current approaches to treating depression rely almost entirely on the subjective recollections of depression sufferers. This is an important step for obtaining objective and precise measurements that guide both diagnosis and treatment."

The study, which is part of UCLA's Depression Grand Challenge, hopes to unearth genetic and environmental factors contributing to depression. It also hopes to understand better the changes that depression causes in the brain and body.



9 Comments

DAalseth 6 Years · 3068 comments

That's very good news. One of the most difficult issues with depression is getting the patient to recognize it. Even if they think they might be depressed, the illness itself keeps them from seeking treatment. Potentially having a device see some symptoms and tell the wearer, "You might be depressed. Might want to see someone," or something like that could be very helpful. It could be analogous to the people who have heart issues that used to just say "Oh it's nothing, it's just indigestion, it'll get better." Now they have their watch say "You might have A-Fib," and they go see their doctor.

lojack 10 Years · 28 comments

True, anything that can help with people's mental well being is always a plus.

The Pac-12 snark in me though wants to say that UCLA is depressed because they're not Cal or USC... :wink: 

DAalseth 6 Years · 3068 comments

lojack said:
The Pac-12 snark in me though wants to say that UCLA is depressed because they're not Cal or USC... :wink: 

LOL. I was a U of OR Duck so I'm laughing with you.

wood1208 10 Years · 2939 comments

More power to Apple. Outcome of this study can long way in identifying and a tool to treat depression.

GeorgeBMac 8 Years · 11421 comments

The times are changing -- or more specifically, medical thinking on depression has been evolving:
For too long the healthcare system saw depression as being treated with drugs.   But, it is now widely accepted that therapy is as effective as drugs in treating this condition.  And, that the best therapy is a combination of the two:  that the whole is greater than the sum of its parts.

But, what is now emerging is that physical activity can also be effective in treating the condition.   The conundrum though is that it's hard to get a person with clinical depression to get out walking, running, cycling, etc.

Perhaps a more relevant question might be:   Can physical activity help to prevent clinical depression from forming -- and just how effective is it?